Description
Product Description
MOTS-c (a mitochondrially encoded 16-amino-acid peptide) is an endogenous microprotein expressed during physical exertion and metabolic stress. In preclinical models, it activates AMPK, improves glucose uptake, fatty acid metabolism, and physical performance, while supporting “healthspan” parameters in aging animals.
A short peptide encoded within the mitochondrial 12S rRNA gene (sORF), which under stress translocates to the nucleus and regulates genes with ARE elements related to antioxidant and metabolic adaptation.
Its expression increases during physical exercise, and exogenous administration improves endurance in mouse models of different ages.
Specifications
Technical Specifications
| Molecular Weight | 3357.9 Da |
| CAS | 1627580-64-6 |
| Form | Lyophilized powder |
| Purity (HPLC) | ≥99% |
| Single Impurity | ≤0.1% |
| Water Content | ≤0.5% |
| Peptide Content | ≥99% |
| Endotoxin | ≤0.1 EU/mg |
Storage
Storage and Handling
Storage Conditions
Store in a refrigerator (2-8°C) for up to 28 days after reconstitution.
Solubility
Soluble in bacteriostatic water.
Precautions
Always wear appropriate protective equipment when working with peptides.
Avoid repeated freeze-thaw cycles.
Use sterile techniques for reconstitution.
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